Worldwide Soccer Manager 2007 is the third entry in the soccer management series. Numerous new features have been introduced in this installment. These include a new default GUI created with the aid of user feedback in an attempt to make it more user friendly.
The game also includes pre-match team talks. In the previous edition, only half-time and full-time team talks could be given. The game has also increased functionality of the half-time team talk, managers can now target individual opposition players for special attention, such as instructing players to close them down or always to tackle them with force.
Last.fm Type in the name of a favorite artist and, in a matter of seconds, music by that artist (and similar artists) will be streaming to your desktop — and it will keep playing as long as that browser window stays open. If you take the time to register and download the last.fm application, the service will dig deeper into your musical life, hook you up with its rapidly-expanding social network and match you with other users who share your musical tastes. Every time you play a song on your computer, last.fm takes note, adding the metadata to your profile. These "scrobbles" are shared with those you designate as your friends; they also help make last.fm a better DJ. MOG, another music site-turned-social network, works in a similar way, keeping tabs on what you listen to, making recommendations and connecting you to other "moggers" who share your tastes. MOG TV (click the Watch tab on the home page) adds music video mashups to the mix. Pandora, another personalized radio service — and a Time.com 2006 best-site pick — recently launched a mobile version that turns your Sprint cell phone into an MP3 jukebox for $3 a month. Use your handset's Web browser to go to Pandora.com to download it.
The Audioscrobbler and Last.fm teams began to work closely together, both teams moving into the same offices in Whitechapel, London, and by 2003 Last.fm was fully integrated with Audioscrobbler profiles. Input could come through an Audioscrobbler plugin or a Last.fm station. The sites also shared many community forums, although a few were unique to each site. The old Audioscrobbler site at the audioscrobbler.com domain name was wholly merged into the new Last.fm site on 9 August 2005. Audioscrobbler.net was launched as a separate development-oriented site on 5 September 2005. However, at the very bottom of each of the Last.fm pages there was an Audioscrobbler "slogan", which changes each time the page is refreshed. Based on well-known sayings or advertisements, these originally appeared at the top of the Audioscrobbler website pages and were all created and contributed by the original site members.
An update to the site was made on 14 July 2006, which included a new software application for playing Last.fm radio streams and for logging of tracks played with other media players. Other changes included the improvement of the friends system and updating it to require a two-way friendship, the addition of the Last.fm "Dashboard" where users can see on one page relevant information for their profile, expanded options for purchasing music from online retailers and a new visual design for the web site (including an optional black colour scheme). The site began expanding its language base on 15 July 2006, with a Japanese version. Currently, the site is available in German, Spanish, French, Italian, Polish, Portuguese, Swedish, Russian, Turkish and Simplified Chinese. In late 2006, the site won Best Community Music Site at the BT Digital Music Awards in October. Last.fm also teamed with EMI on Tuneglue-Audiomap. In January 2007 it was nominated for Best Website at the NME Awards.
At the end of April 2007, rumours of negotiations between CBS and Last.fm emerged, suggesting that CBS intended to purchase Last.fm for about £225 million ($449 million). In May 2007 it was announced that Channel 4 Radio was to broadcast a weekly show called Worldwide Chart reflecting what Last.fm users around the world were listening to. On 30 May 2007, it was announced that Last.fm had been bought by CBS for £140 million with Last.fm's current management team staying in place. In July 2008, the "new generation" Last.fm was launched featuring a completely new layout, color scheme, and several new features, as well as some old ones removed. This was, however, met with dissatisfaction amongst some users, who complained about the "ugly and non-user-friendly layout", bugs, and slowness. Still, a month after the redesign a CBS press release credited the redesign with generating a 20% growth in the site's traffic.
On 12 April 2010, Last.fm announced that they would be removing the option to preview entire tracks, instead redirecting to sites such as the free Hype Machine and pay-to-listen MOG for this purpose. This provoked a large negative reaction from some in the Last.fm user community who perceived the removal as hindering the ability of lesser-known and unsigned artists to gain exposure for their music and general enjoyment of the site. A new "Play direct from artist" feature was introduced soon after, which allowed artists to select individual tracks for users to be able to stream in full.
In March 2012, Last.fm was breached by hackers and more than 43 million user accounts were compromised. The full extent of the hack, and its connection to similar attacks against Tumblr, LinkedIn and Myspace in the same time frame, were not confirmed until August 2016. The passwords were encrypted using an outdated, unsalted MD5 hash. Last.fm made users aware of the attack in June 2012.
In 2016, Music Manager was discontinued and music uploaded to the site by musicians and record labels became inaccessible; post-Spotify integration they could still be played and downloaded where the option was given, but following the change artists themselves were unable to access their songs in the Last.fm catalogue.
Under the terms of the station's "radio" license, listeners may not select specific tracks (except as previews), or choose the order in which they are played, although any of the tracks played may be skipped or banned completely. The appropriate royalties are paid to the copyright holders of all streamed audio tracks according to the law in the UK. The radio stream uses an MP3 stream encoded at 128 kbit/s 44.1 kHz, which may be played using the in-page Flash player or the downloaded Last.fm client, but other community-supported players are available as well as a proxy which allows using a media player of choice.
An "in-page" player is provided automatically for all listeners with HTML5-enabled browser or Adobe Flash installed on their computers. However, it is necessary to download and install the Last.fm client if a user also wishes information about played tracks from their own digital music collection to be included in their personal music profile.
The player displays the name of the station and track currently playing, the song artist, title and track length as well as album details, the artist's photo and biographical details, album cover art when available, lists of similar artists and the most popular tags and top fans. There are several buttons, allowing the user to love, skip, or ban a song. The love button adds the song to the user's loved tracks list; the ban button ensures that the song will not be played again. Both features affect the user's profile. The skip button does not. Other buttons allow the user to tag or recommend the currently playing track. Other features offered by the application are: minor editing of the user's profile including removing recently played artists and songs from the loved, banned, or previously played track lists; lists of friends and neighbours, lists of tags and a list of previously played radio stations. Users can also open their full Last.fm profile page directly from the player.
In addition to Last.fm automatically tracking music played via Last.fm's radio, users can also contribute (scrobble) listening data to their Last.fm profile from other streaming sites or by tracking music played locally on their own personal devices. Scrobbling is possible with music stored and played locally via software on devices such as PCs, mobile phones, tablets, and standalone (hardware) media players. Indeed, these were the only methods of scrobbling listening data both before and after the existence of the Last.fm radio service. Certain sites and media players have the ability to upload (scrobble) listening data built-in, for others users must download and install a plugin for their music player, which will automatically submit the artist and title of the song after either half the song or the first four minutes have played, whichever comes first. When the track is shorter than 30 seconds (31 seconds in iTunes) or the track lacks metadata (ID3, CDDB, etc.), the track is not submitted. To accommodate dial-up users or those listening to music while offline, caching of the data and submitting it in bulk is also possible.
Article Source: Exploiting Amoeboid and Non-Vertebrate Animal Model Systems to Study the Virulence of Human Pathogenic Fungi Mylonakis E,Casadevall A,Ausubel FM (2007) Exploiting Amoeboid and Non-Vertebrate Animal Model Systems to Study the Virulence of Human Pathogenic Fungi.PLOS Pathogens 3(7): e101.
We announce here the completion of the fully assembled and annotated genome sequence of a nonmucoid derivative of this RmInt1 intronless S. meliloti strain. Sequencing was performed on a GS FLX Titanium platform (Roche Diagnostics) at MACROGEN, Inc. (Korea), with both shotgun and 3 kb paired-end libraries, resulting in 180-fold genome coverage. The raw sequence data met the quality standards of the Genomes OnLine Database (GOLD) (23). GS FLX data processing was performed with Roche GS FLX software (v2.6). Assembly was achieved with the GS De Novo Assembler (v2.6), resulting in 10 scaffolds (>115 kb each; N50, 925,704 bp). Intrascaffold and interscaffold gaps were closed by the detailed observation of relevant sequencing reads with the Geneious R7 software platform (24). 2b1af7f3a8